TRAF3IP2 anticorps (AA 554-568)

N° du produit ABIN1886888

L’anticorps Lapin Polyclonal anti-TRAF3IP2 a été validé pour WB, ELISA et IHC. Il convient pour détecter TRAF3IP2 dans des échantillons de Humain.

Aperçu rapide pour TRAF3IP2 anticorps (AA 554-568) (ABIN1886888)

Antigène: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3IP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TRAF3IP2 anticorps

Épitope: AA 554-568

Purification: Affinity chromatography purified via peptide column

Immunogène: Synthetic peptide corresponding to amino acids 554 to 568 of human CIKS.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur TRAF3IP2

Antigène: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Autre désignation: CIKS

Sujet: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses.NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli.NF-kappaB associates with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity.IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma.A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappaB activator 1).CIKS directly interacts with IKKgamma.CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK).These results indicate that CIKS/Act1 is involved in the inflammation and stress responses.CIKS/Act1 is ubiquitously expressed in human tissues.
Synonyms: Act1

Poids moléculaire: 63 kDa

Pathways: Production of Molecular Mediator of Immune Response